Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture
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چکیده
منابع مشابه
tumor-like phenotype in three-dimensional basement membrane culture
Background: MCF-10A cells are near diploid and normal human mammary epithelial cells. In three-dimensional reconstituted basement membrane culture, they undergo a well-defined program of proliferation, differentiation, and growth arrest, forming acinar structures that recapitulate many aspects of mammary architecture in vivo. The pre-malignant MCF-10AT cells and malignant MCF-10CA1a lines were ...
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ژورنال
عنوان ژورنال: Cancer Cell International
سال: 2009
ISSN: 1475-2867
DOI: 10.1186/1475-2867-9-7